Diabetic retinopathy - pathophysiology

Pathophysiology of diabetic retinopathy.

After a brief analysis of the pathological picture of diabetic retinopathy, of which only the topographical distribution of the vascular lesions appears to be specific, the results obtained with 2 new methods of study of the retinal circulation, are presented. These methods are vitreous fluorophotometry and fluorometric determination of segmental retinal blood flow. Vitreous fluorophotometry ha...

Pathophysiology of Diabetic Retinopathy

Diabetes is now regarded as an epidemic, with the population of patients expected to rise to 380 million by 2025. Tragically, this will lead to approximately 4 million people around the world losing their sight from diabetic retinopathy, the leading cause of blindness in patients aged 20 to 74 years. The risk of development and progression of diabetic retinopathy is closely associated with the ...

Diabetic Retinopathy – An Update on Pathophysiology, Classification, Investigation and Treatment

Neurovascular Interaction and the Pathophysiology of Diabetic Retinopathy

Diabetic retinopathy (DR) is the most severe of the several ocular complications of diabetes, and in the United States it is the leading cause of blindness among adults 20 to 74 years of age. Despite recent advances in our understanding of the pathogenesis of DR, there is a pressing need to develop novel therapeutic treatments that are both safe and efficacious. In the present paper, we identif...

New Developments in the Pathophysiology and Management of Diabetic Retinopathy

Diabetes mellitus is a chronic disorder of glucose metabolism with serious multisystem complications including microvas-cular dysfunction such as retinopathy, nephropathy, and neuropathy. The prevalence of diabetes has been rising in the last few decades and affecting working age population which reflects the socioeconomic burden on different communities and a major challenge to the current hea...